President Joe Biden is set to sign 10 executive orders to boost the fight against Covid which has ravaged the US.
Vaccination will be accelerated and testing increased. Emergency legislation will be used to increase production of essentials like masks.
In a break with former President Donald Trump, the policy stresses a national strategy rather than relying on states to decide what is best.
The moves comes a day after Mr Biden was sworn in as the 46th president.
The Trump administration was widely accused of failing to get to grips with the pandemic.
In terms of total deaths from coronavirus, the US is the worst-hit country with more than 406,000 lives lost according to Johns Hopkins University. Nearly 24.5m have been infected.
BDST: 2001 HRS, JAN 21, 2021